Med-tech venture builders since 1997
Seed One takes breakthrough research out of the university lab, secures the IP, forms the company, hires the team and takes it to market. Not investors. Builders.
We build companies in biotechnology, biodefense and medical devices.
[ 01 ] Our mission
We take breakthrough research out of the university lab and turn it into companies that reach patients, with the IP, the team and the capital built in from day one.
Most venture firms wait for a pitch deck. We start with the science, buy it, protect it and build the business around it.
Then we run the company ourselves, with purpose, speed and might, until it can stand on its own.
A breakthrough that nobody has built a company around yet. That is where we begin.
Companies forged by our team
[ 02 ] Method
No committees. No politics. Just founders building with purpose, speed, and might.
What we doStage
01We scour university research for breakthrough science with a clear path to patients or industry.
Stage
02We acquire the technology and lock down the intellectual property.
Stage
03We incorporate the company, put in early-stage capital and set brutal milestones.
Stage
04We hire the team, often the scientists who developed the work, and act as the hands-on management until it scales.
Stage
05We take the product to market and the company to its exit: public listing, strategic sale or standalone growth.
[ 03 ] Case studies
We've built more than a dozen companies from the ground up. Here are three of them:
See the full portfolioNon-invasive fat reduction, from lab bench to a $115 million IPO.
Founded by Scott Wolf around a controlled-cooling breakthrough. FDA approved in 2010, listed in 2011, sold in 45 international markets and now a household name.
The anthrax antitoxin the United States keeps in reserve.
Built by Jeff Wolf on a technology for removing blood-borne pathogens. Its antitoxin ANTHIM is licensed in the United States and Canada as a medical countermeasure.
Relief for millions with chronic ENT conditions, without surgery.
Founded by Scott Wolf. Temperature-controlled technology gives ENT physicians a reliable alternative to invasive surgery. More than 150,000 patients treated to date.
[ 04 ] Impact
One model, repeated: find the science, acquire it, forge a pathbreaking company based on the science.
See the portfolioCompanies forged
Built from breakthrough research, from first patent to exit.
Exits
Public and strategic.
Years building
Building companies for over 2 decades.
Raised
Companies forged by Seed One have raised over $1 billion from inception to exit.
Focus areas
Biotechnology, biodefense and medical devices.
[ 05 ] The people behind the progress
Scientific curiosity. Commercial experience. A hands-on commitment to forging great companies.
Meet the team01
Managing Director
Founder of Seed One. A company builder with more than a dozen companies from breakthrough research, including Elusys, Heat Biologics and Scorpius.
02
Managing Director
Medical device inventor and founder of companies including ZELTIQ Aesthetics, Aerin Medical and Cardiac Dimensions.
03
Director
Immunologist with a decade of preclinical drug development across biologics, small molecules and vaccines.
04
Director
Government affairs and business development, connecting scientific ambition with strategic opportunity.
[ 06 ] Contact · Have a breakthrough?
If you have technology that could reshape an industry, we want to hear from you.
